In order to compare the nutrient composition of wild and farmed Thamnaconus septentrionalis， 10 （each as an independent sample） wild （20.0-21.7 cm in length and 120.95-170.66 g in weight） and 10 farmed Thamnaconus septentrionalis （21.0-23.4 cm in length and 124.08-184.85 g in weight） were used in this study， and the morphological indexes， proximate composition， fatty acid profile and amino acid profile were analysed and compared. The results were as follows： the hepatosomatic index and viscerosomatic index of the farmed group were significantly higher than those of the wild group， and there was no significant difference in condition factor. The crude protein content of the muscle of Thamnaconus septentrionalis ranged from 18.5% to 20.2%， and the crude lipid content ranged from 0.8% to 1.1%. The crude protein and crude fat contents of the muscle of the farmed group were significantly higher than those of the wild group， and there was no significant difference in moisture content. The ash content of the whole fish and liver of the farmed group was significantly lower than that of the wild group. The fatty acid composition of whole fish was similar between the farmed and wild groups. Muscle DHA and EPA contents （% total fatty acids） were 20.2%-24.7% and 11.4%-15.8%， respectively. The contents of saturated fatty acids， 20：4n-6 and DHA in muscle were significantly lower in the farmed group compared to the wild group， but the EPA content was significantly higher than that in the wild group； while the differences in the contents of long-chain polyunsaturated fatty acids and EPA+DHA were not significant. A total of 18 amino acids were detected in the whole fish and muscle of wild and cultured Thamnaconus septentrionalis. The amino acid composition of the whole fish was similar between wile and farmed fish， but the total amount of essential amino acids in the muscle of the farmed group was significantly higher than that of the wild group. Among the essential amino acids， the contents of isoleucine， leucine， phenylalanine， and lysine in the muscle of the cultured group were significantly higher compared to the wild group. In conclusion， the nutritional value of Thamnaconus septentrionalis is higher， and the nutritional quality of farmed Thamnaconus septentrionalis is higher than that of wild Thamnaconus septentrionalis， as evaluated by the contents of protein， lipid， EPA and essential amino acids in muscle.